Jorge Laborda

Your defenses against the coronavirus Jorge Laborda

This book is intended as a brief introduction to the fascinating mechanisms by which the immune system keeps microorganisms at bay. The book is structured as a story in which the organism is under attack. To defend itself, it sets up different cellular actors and molecular mechanisms, which we are introducing as history develops. In this way, the understanding of the reasons for the various defense mechanisms that the immune system puts in place is facilitated. It also addresses the mechanisms of action of vaccines and different types of vaccines that are known, as well as some of fascinating reasons why microorganisms can escape from the the action of the immune system and vaccines can be ineffective. The knowledge gained from reading the first seven chapters are applied in the last one to analyze why the new SARS-CoV-2 virus, causing COVID-19 disease, can behave in such a different way depending on how well or how badly the defense mechanisms that each person has, according to the state of health, the age or genetic background work. These mechanisms should be effective but, on too many tragic occasions, they are not. Reading this book will arm us better to understand the reasons for pandemics and the reasons why some overcome infectious diseases and others do not.