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Cell-free Circulating Dna: Purification and Analysis Techniques Kristina Warton
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Cell-free Circulating Dna: Purification and Analysis Techniques
Kristina Warton
Circulating cell-free DNA is poised to transform cancer diagnosis and care; however, it carries technical challenges such as low abundance, fragmentation and sensitivity to biospecimen handling. Development of clinically useful assays hinges on understanding the unique technical aspects of working with cell-free DNA as a substrate. This book provides an in-depth summary of the technical issues impacting cell-free DNA purification from blood plasma and analysis in a cancer context, including design of PCR assays, sequencing library preparation and methylation analysis. Emerging fields such as extracellular vesicles and blood nucleases are also covered, as well as basic biology and considerations pertinent to biobanking.
300 pages
| メディア | 書籍 Hardcover Book (ハードカバー付きの本) |
| リリース済み | 2022年8月22日 |
| ISBN13 | 9789811244674 |
| 出版社 | World Scientific Publishing Co Pte Ltd |
| ページ数 | 296 |
| 寸法 | 237 × 158 × 23 mm · 572 g |
| 言語 | 英語 |
| 編集者 | Samimi, Goli (National Cancer Institute, USA) |
| 編集者 | Warton, Kristina (University of New South Wales, Australia) |
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